Research Paper Volume 14, Issue 4 pp 1910—1931

Expression profile and prognostic values of Chromobox family members in human glioblastoma


Figure 7. Predicted protein-protein interactions, functions, and pathways of CBXs and their co-expressed genes in GBM. (A) Protein-protein interaction (PPI) enrichment analysis of the 103 co-expressed genes of CBXs was constructed in cBioPortal and Cytoscape. The color of nodes: low values to bright colors; high values to dark colors. The thickness of edges: low values to fine edges; high values to thick edges. (B) Gene Ontology (GO) functional enrichment analysis of CBXs co-expressed genes (WebGestalt), including biological process, cellular components, and molecular functions. (C) Kyoto Encyclopedia of Genes and Genome (KEGG) analysis of CBXs co-expressed genes (WebGestalt).