Research Paper Volume 14, Issue 4 pp 1941—1958

Fusobacterium nucleatum promotes liver metastasis in colorectal cancer by regulating the hepatic immune niche and altering gut microbiota


Figure 3. Fusobacterium nucleatum regulates the levels of inflammatory cytokines in mice plasma. (AK) Concentrations of the pro-inflammatory cytokines, (A) Interferon-gamma (IFN-γ), (B) tumor necrosis factor-α (TNF-α), (C) IL6, (D) IL12, (E) IL17A, (F) chemokine (C-X-C) motif ligand (CXCL1), (G) IL9, (H) macrophage chemoattractant protein-1(MCP-1), (I) Eotaxin, (J) IL10, (K) IL1α in murine plasma were detected by the Bio-Plex Pro Mouse Cytokine Array kit. Data are presented as mean ± standard deviation (n=5 per group). *P < 0.05, **P < 0.01, and ***P < 0.001; unpaired Student’s t-test.