Research Paper Volume 14, Issue 4 pp 1941—1958

Fusobacterium nucleatum promotes liver metastasis in colorectal cancer by regulating the hepatic immune niche and altering gut microbiota

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Figure 3. Fusobacterium nucleatum regulates the levels of inflammatory cytokines in mice plasma. (AK) Concentrations of the pro-inflammatory cytokines, (A) Interferon-gamma (IFN-γ), (B) tumor necrosis factor-α (TNF-α), (C) IL6, (D) IL12, (E) IL17A, (F) chemokine (C-X-C) motif ligand (CXCL1), (G) IL9, (H) macrophage chemoattractant protein-1(MCP-1), (I) Eotaxin, (J) IL10, (K) IL1α in murine plasma were detected by the Bio-Plex Pro Mouse Cytokine Array kit. Data are presented as mean ± standard deviation (n=5 per group). *P < 0.05, **P < 0.01, and ***P < 0.001; unpaired Student’s t-test.