Research Paper Volume 14, Issue 5 pp 2113—2130

Human endothelial cells promote arsenic-transformed lung epithelial cells to induce tumor growth and angiogenesis through interleukin-8 induction


Figure 1. Human endothelial cells greatly promoted As-T cells to induce tumor growth. As-T cells and human dermal microvascular endothelial cells (HMVECs) were trypsinized, mixed in a 1:9 ratio with serum-free medium, and carried by the PLGA sponges for the implantation onto the CAM of 8 days old chicken embryos. As-T cells alone were used as a control. The tumors were harvested 12 days after the implantation. (A) Representative tumors. Scale, 1 mm. (B) The weight of plugs (n = 7 for each group). ***p < 0.001 compared with As-T alone control group.