Research Paper Volume 14, Issue 5 pp 2287—2303

MafK accelerates Salmonella mucosal infection through caspase-3 activation

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Figure 5. MafK promotes epithelial cell apoptosis following Salmonella oral challenge. (A) Immunofluorescence was performed on cecum sections derived from WT and MafK Tg mice on Day 2 post Salmonella oral infection to examine proliferating cells (Ki-67). (B) Cell death was identified in the cecum by TUNEL staining. Levels of cleaved caspase-3 expression in cecum lysates on Day 2 (C) and 6 h (D) after Salmonella oral infection were determined by western blotting.