Research Paper Volume 14, Issue 5 pp 2418—2431

miRNA-29a inhibits atherosclerotic plaque formation by mediating macrophage autophagy via PI3K/AKT/mTOR pathway


Figure 5. MiR-29a increases the expressions of M2-like macrophages markers (Arginase-1, Mrc-1 and IL-10) and decreases the expressions of M1-like macrophages markers (iNOS, IL-1β and IFN-γ) in vivo. (A) The expressions of these proteins are detected by immunofluorescence assay. (B) The relative fluorescence intensities of Arginase-1, Mrc-1, IL-10, iNOS, IL-1β and IFN-γ. Data are expressed as the mean ± SD. P < 0.05. Model group vs. miR-29a group; miR-29a group vs. anti-miR-29a group.