Research Paper Volume 14, Issue 5 pp 2418—2431

miRNA-29a inhibits atherosclerotic plaque formation by mediating macrophage autophagy via PI3K/AKT/mTOR pathway


Figure 7. MiR-29a elevation enhances macrophage autophagy. (A) Administration of miR-29a significantly up-regulates the expression of LC3II in macrophages. (B) The quantitative analysis of relative fluorescence intensity reveals that the expression of LC3II is increased, but it was significantly decreased by anti-miR-29a in miR-29a group. Data are expressed as the mean ± SD. P < 0.05. Model group vs. miR-29a group; miR-29a group vs. anti-miR-29a group.