Adipose-derived mesenchymal stem cells may reduce intestinal epithelial damage in ulcerative colitis by communicating with macrophages and blocking inflammatory pathways: an analysis <i>in silico</i>

Nan Zhang; Yixuan Chen; Chengyu Huang; Mengxin Wei; Ting Li; Yufeng Lv; Qiong Song; Shaowen Mo

doi:doi:10.18632/aging.203964

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Research Paper Volume 14, Issue 6 pp 2665—2677

Adipose-derived mesenchymal stem cells may reduce intestinal epithelial damage in ulcerative colitis by communicating with macrophages and blocking inflammatory pathways: an analysis in silico

Figure 5. Proposed mechanism about ADMSCs may alleviate UC. (A) The proposed mechanism that macrophages may contribute to UC by communicating with enterocytes via ligand-receptor interactions. (B) Proposed mechanism of how ADMSCs may alleviate UC by communicating with macrophages and blocking inflammation. ADMSCs: adipose-derived mesenchymal stem cells. UC: ulcerative colitis.