Research Paper Volume 14, Issue 6 pp 2748—2757

Ischemic postconditioning protects nonculprit coronary arteries against ischemia-reperfusion injury via downregulating miR-92a, miR-328 and miR-494


Figure 6. IP inhibited OGD/R-induced apoptosis of HUVECs via downregulating mRNA AT1, Cx43 and β-tubulin. (A, B) Flow cytometric analysis was performed to detect the apoptosis of HUVECs. (CF) Western blot assay was used to detect the expression of Bax, Bcl-2 and cleaved caspase 3 in HUVECs. (GI) RT-qPCR was performed to detect the expression of AT1, Cx43 and β-tubulin. *P<0.01, **P<0.01 compared with the sham group; #P<0.01, ##P<0.01 compared with the IR group.