Research Paper Volume 14, Issue 7 pp 2945—2965
E-cadherin deficiency promotes prostate macrophage inflammation and bladder overactivity in aged male mice
Figure 5. Effects of age on inflammation in the murine prostate. (A) Quantification of CD68+ macrophages in the prostate from control mice at 6 and 24 months of age. Abbreviations: vp: ventral prostate; lp: lateral prostate; dp: dorsal prostate; ap: anterior prostate. (B) CD68 immunostaining (brown) in transverse sections of prostate ventral lobes at 6 and 24 months of age. (C) Quantification of CD3+ T-cells in the prostate from control mice. (D) CD3 immunostaining (brown) in transverse sections of prostate ventral lobes. Black arrow indicates CD+ cell. (E) Quantification of CD19+ B-cells in the prostate from control mice. (F) CD19 immunostaining (brown) in transverse sections of prostate ventral lobes. Data represent mean ± S.D, number of mice in each group in parentheses. Lobes which had been washed away during staining process were not quantified. Original magnification, 40×, inset 40×. *p < 0.05, **p < 0.01. Scale bars indicate 50 μm in 40×.