Research Paper Volume 14, Issue 18 pp 7378—7389

Fasudil inhibits hepatic artery spasm by repressing the YAP/ERK/ ETA/ETB signaling pathway via inhibiting ROCK activation


Figure 6. Schematic diagrams of this study. Graphic illustration of the ROCK/ERK1/2/ETA/ETB/YAP signaling pathway after treatment with Fasudil. Fasudil inhibited the RhoA/ROCK signaling pathway to repress ERK1/2 activation and YAP/ETA/ETB signaling cascades, thus suppressing HA spasm.