Research Paper Volume 14, Issue 16 pp 6656—6667
Gene expression profile of human colorectal cancer identified NKTR as a biomarker for liver metastasis
Figure 1. An overview of the ADA method. 1. “FindGeneSignature” used a grid search procedure that searched through various tradeoffs of the mean difference test and t-test. 2. “EstimatePerformance” was used to estimate model performance (ROC curve). 3. “FindImportantGenes” is a wrapper procedure that iteratively collects generated gene signatures and removes these genes from further runs.