Research Paper Volume 14, Issue 16 pp 6689—6715
Prognostic alternative splicing events related splicing factors define the tumor microenvironment and pharmacogenomic landscape in lung adenocarcinoma
Figure 10. Drug sensitivity analysis and small molecule drugs screening. (A) Low SFscore is more sensitive to sorafenib, paclitaxel, sunitinib, cisplatin, docetaxel, Etoposide, vinorelbine, gemcitabine, gefitinib and vorinostat (p < 0.001). (B) Screening of small molecule drugs based on SFscore. (C) Network construction of target protein and five small molecule drugs. (D–H) Druggable pharmacophore models of five small molecule drugs.