Research Paper Volume 14, Issue 16 pp 6740—6755

Sulforaphane inhibits angiotensin II-induced cardiomyocyte apoptosis by acetylation modification of Nrf2


Figure 6. SFN activates Nrf2 through inhibiting HDACs expression and activity. The HDACs activity kit was used to detect the global HDACs activity (A). Western blot was used to detect the expression of HDAC2, HDAC3, HDAC5 (B). TSA, a deacetylase inhibitor, was used as a positive control. Data were presented as the mean SD (n = 3). *P < 0.05 vs control; # P < 0.05 vs Ang II.