Research Paper Volume 14, Issue 16 pp 6780—6795
High expression of CCNB1 driven by ncRNAs is associated with a poor prognosis and tumor immune infiltration in breast cancer
Figure 5. Expression of CCNB1 in different molecular subtyping of BC. (A) The relative expression of CCNB1 in luminal A, luminal B, Her2+, basal like and MCF 10A cell lines. CCNB1 expression was higher in the four molecular subtyping of BC (luminal A, luminal B, Her2+, basal like) than in the normal group. (B) Compared with the MCF 10A cell line, CCNB1 was up-regulated in luminal A, luminal B and basal-like cell lines, but down-regulated in Her2+ cell line, as verified by qRT-PCR. *p < 0.05, **p < 0.01, ***p < 0.001. Abbreviation: BC: breast cancer.