Research Paper Volume 14, Issue 16 pp 6780—6795
High expression of CCNB1 driven by ncRNAs is associated with a poor prognosis and tumor immune infiltration in breast cancer
Figure 6. Related genes and signaling pathways affected by CCNB1. (A) DEGS: heat map. According to the different expression levels of CCNB1, they are divided into two groups: high expression (Green in the right half of the image) and low (Pink in the left half of the image) expression. The abscissa is the sample, and the ordinate is the gene name. (B) Go and KEGG analysis. (a) Go analysis demonstrated that CCNB1 and genes significantly associated with CCNB1 alterations mainly enriched extracellular matrix organization, leukocyte migration and extracellular structure organization. (b) The major enriched pathways were those connected with cell cycle, AMPK, PPAR signaling pathway and TGF signaling beta pathway according to the KEGG analysis. (C) The genes that are strongly linked to CCNB1.