Research Paper Volume 14, Issue 17 pp 6936—6956

Clinical significance for diagnosis and prognosis of POP1 and its potential role in breast cancer: a comprehensive analysis based on multiple databases


Figure 2. Mutation status of POP1 gene based on cBioPortal and the relationship between POP1 expression and clinical features of BC based on UALCAN databases. (A) Mutation analysis of the cBioPortal database showed that POP1 was the fourth most common mutation in BC. (B) UALCAN database also suggested that POP1 was more highly expressed in BC than in normal breast tissue. (C, D) Subgroup analysis verified that POP1 expression was higher in BC than in normal tissues regardless of stage or lymph node metastasis status.