Research Paper Volume 14, Issue 17 pp 6936—6956

Clinical significance for diagnosis and prognosis of POP1 and its potential role in breast cancer: a comprehensive analysis based on multiple databases


Figure 6. Gene Set Enrichment Analysis (GSEA) and Gene Ontology (GO) of corresponding functions and signaling pathways associated with POP1 expression. (AH) The POP1 expression was significantly correlated with the E2F target, G2M checkpoint, interferon-gamma response, mitTORC1 signaling, and MYC targets. (I) The differentially expressed genes between the high- and low-POP1 groups were mainly enriched in organelle fission, nuclear division, and chromosome segregation. Abbreviations: GSEA, Gene set enrichment analysis; GO, Gene Ontology.