Research Paper Volume 14, Issue 17 pp 7003—7013
UBE2C mediated radiotherapy resistance of head and neck squamous cell carcinoma by regulating oxidative-stress-relative apoptosis
Figure 1. UBE2C is over-expressed in HNSCC after radiation and associated with the poor prognosis. (A) The expression of UBE2C was different in different subclasses (Tumor group, N=519. Normal group, N=44.). (B) The different survival probability between the high expression and low/medium expression of UBE2C were shown (p=0.025). (C) RT-PCR result of UBE2C gene expression in CAL27 after 0/2 Gy radiation. (D) Western blot result of UBE2C protein expression in CAL27 after 0/2 Gy radiation. (E) Cell viability of CAL27 after 0/2 Gy radiation. (F) Cell colony formation assay of CAL27 after 0/2 Gy radiation. *P < 0.05, **P < 0.01, ***P < 0.001 versus the control.