Research Paper Volume 14, Issue 17 pp 6859—6886

Extracellular microRNA and cognitive function in a prospective cohort of older men: The Veterans Affairs Normative Aging Study


Figure 2. Volcano plot of plasma miRNAs associated with baseline MMSE score. Estimates (pooled from ten imputed datasets) from linear models adjusted for age, education, alcohol consumption, and smoking status. The 5 and 6 most statistically significant extracellular miRNAs with negative and positive beta estimates, respectively, are labeled. The 2 extracellular miRNAs significant at FDR q-value < 0.05 are plotted in red. Abbreviations: FDR: False Discovery Rate; MMSE: Mini-Mental State Examination; n.s.: not significant.