Research Paper Volume 15, Issue 1 pp 53—69
miR-6742-5p regulates the invasion and migration of lung adenocarcinoma cells via mediating FGF8/ERK12/MMP9/MMP2 signaling pathway
Figure 6. miR-6742-5p inhibited the migratory capability of LUAD cell. Wound healing assay showed that miR-6742 mimic (OE) significantly increased and miR-6742 inhibitor (KD) reduced wound closure and its quantifications in H522 Cells; (A) 24hours *P=0.0152miR-6742-5p OE group vs NC group;**P=0.0015miR-6742-5p KD group vs NC group; 48hours **P=0.0092 miR-6742-5p OE group vs NC group;*P=0.0281 miR-6742-5p KD group vs NC group (B) 24hours **P=0.0006miR-6742-5p OE group vs NC group;**P=0.0001miR-6742-5p KD group vs NC group; 48hours **P=0.0001 miR-6742-5p OE group vs NC group;**P=0.0002 miR-6742-5p KD group vs NC group.