Research Paper Volume 14, Issue 18 pp 7300—7327

Age-related metabolic and neurodegenerative changes in SAMP8 mice


Figure 11. Hyperphosphorylation of tau protein in the hippocampi of SAMP8 mice (A) western blots, (B) their quantification, and (C) immunofluorescence of p-tau [Ser396] at CA1 area of the hippocampus. Data are mean ± SEM, analyzed by 2-way ANOVA with Bonferroni post test. Significance is *P < 0.05, **P < 0.01 and ***P < 0.001; * SAMP8 compared to SAMR1, + age-dependent changes in SAMR1, and # age-dependent changes in SAMP8. n = 4-5 mice per group.