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Research Paper Volume 14, Issue 20 pp 8302—8320

Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats

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Figure 3. Tanshinone IIA (TIIA) decreased Bax and increased Bcl-2. The expression of Bax and Bcl-2 in mRNA (A) and protein (B) level. Immunofluorescence results of Bax (green) and Bcl-2 (red) expression in nephridial tissue, the scale bars represent a length of 500 μm on histology (C). *p < 0.05 versus sham group, #p < 0.05 versus IR (obese) group, ∆p < 0.05 versus TIIA (5 mg/kg.d) group, ▲p < 0.05 versus TIIA (10 mg/kg.d) group. (n=3).