Research Paper Volume 14, Issue 20 pp 8411—8436

ZNF320 is a hypomethylated prognostic biomarker involved in immune infiltration of hepatocellular carcinoma and associated with cell cycle

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Figure 3. ZNF320 expression in tumor tissues is associated with poor survival in HCC patients. (A, B) HCC patients with lower expression level of ZNF320 had favorable OS and DSS results from KM plotter (p=0.00084; p=0.027). (C) HCC patients with lower expression level of ZNF320 had favorable OS results from R(p=0.017) (D) ROC curves for the 1-, 3-, and 5-year survival according to the expression level of ZNF320. AUC, area under the curve; ROC, receiver operating characteristic. (E) A forest plot of the results of the multivariate analysis. *, P<0.05; **, P<0.01; ***, P<0.001. HR, hazard ratio; CI, confidence interval; T, tumor; N, node, M, metastasis; OS, overall survival; AIC, Akaike’s information criterion.