Research Paper Volume 14, Issue 20 pp 8411—8436

ZNF320 is a hypomethylated prognostic biomarker involved in immune infiltration of hepatocellular carcinoma and associated with cell cycle


Figure 8. Correlations of ZNF320 expression with immune infiltration level in HCC (TIMER). (A) ZNF320 expression is positively related to tumor purity, infiltrating levels of CD8 +T cells, CD4 + T cells, macrophages, neutrophils and dendritic cells in HCC. (B) ZNF320 CNV affects the infiltrating levels of CD8 + T cells, macrophages, and dendritic cells in HCC. *P < 0.05, ***P < 0.001. (C) Distribution of ZNF320 expression across immune subtypes in LIHC (TISIDB). The different color plots represent the five immune subtypes (C1: wound healing; C2: IFN-gamma dominant; C3: inflammatory; C4: lymphocyte-depleted and C6: TGF-b dominant).