Research Paper Volume 14, Issue 23 pp 9617—9631
A circadian rhythm-related biomarker for predicting prognosis and immunotherapy efficacy in lung adenocarcinoma
Figure 8. The investigation of somatic mutation between the low-risk cohort and high-risk cohort. (A, B) The waterfall plot showed a distinct mutation rate between the low- and the high-risk cohorts. (C, D) The high mutated cohort had a higher risk than the low mutated cohort. (E) TMB was estimated with maftool in R, and ranged from 0.02/MB to 37.54/MB. (F) TMB was significantly elevated in the high risk cohort compared to its counterpart. *P <0.05, **P <0.01, ***P <0.001.