Research Paper Volume 15, Issue 1 pp 193—212
A two-gene random forest model to diagnose osteoarthritis based on RNA-binding protein-related genes in knee cartilage tissue
Figure 7. RNMT and RBM24 were associated with genesis of OA. (A–C) The diagnosis value of RNMT and RBM24 in the training cohort (A), the GSE117999 cohort (B), and the local cohort (C). (D) The mean decrease accuracy (up) and the mean decrease Gini (bottom) of RNMT and RBM24 in the random forest model. (E, F) The qPCR experiments (E) and Western Blotting (F) displayed that RNMT and RBM24 were both down-regulated in the CHON-001 cells treated with 10 ng/mL IL-1β.