Research Paper Volume 15, Issue 4 pp 1177—1198

Figure 2. Different FAM clusters mediated by FAM-related genes. (A) 78 prognostic FAM genes were further selected by Lasso regression algorithm. (B) 8 prognostic FAM-related genes were finally identified applying multivariate Cox regression model. (C) Forest plot visualize the prognostic value of 8 prognostic FAM-related genes. (D) Three distinct FAM clusters were established based on the expression of prognostic FAM genes using Consensus Clustering analysis of the NMF algorithm. Survival analyses for RFS (E) and OS (F) among different FAM clusters in METABRIC-TNBC cohort. (G) Differences in KEGG pathways between the FAM cluster-C1 and FAM cluster-C3. (H) Differences in KEGG pathways between the FAM cluster-C2 and FAM cluster-C3.