Research Paper Volume 15, Issue 5 pp 1496—1523

Identification of fatty acid metabolism-related clusters and immune infiltration features in hepatocellular carcinoma

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Figure 1. Multi-omics landscape of FAM-related genes in HCC based on TCGA cohort. (A) The mutation frequency of 49 FAMs in TCGA-LIHC cohort. Each column of the figure represents an individual patient. (B) The CNV variation frequency of FAMs (Red and green plots separately represent CNV gain and CNV loss). (C) Locations of CNV alterations in FAMs on 23 chromosomes. (D) The mRNA expression levels of 49 FAMs between HCC and normal tissues. Abbreviations: FAM: fatty acid metabolism; HCC: hepatocellular carcinoma; FAMs: fatty acid metabolism-related genes; TCGA: The Cancer Genome Atlas; LIHC: liver hepatocellular carcinoma; CNV: copy number variant. *p < 0.05; **p < 0.01; ***p < 0.001.