Research Paper Volume 15, Issue 5 pp 1543—1563

Identification and integration analysis of a novel prognostic signature associated with cuproptosis-related ferroptosis genes and relevant lncRNA regulatory axis in lung adenocarcinoma

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Figure 7. Survival analysis of potential prognostic biomarkers and identification of the core genes. Results of (A) OS and (B) PFS survival analysis for the potential prognostic biomarkers. (C) Relationship between LIFR expression and OS. (D) Relationship between TFAP2A expression and OS. (E) Relationship between TFAP2A expression and PFS. Correlation studies of potential prognostic genes with MSI, in which (F) CAV1 was significantly associated with MSI, while (G) LIFR was non-significantly associated with MSI as well as (H) TFAP2A was significantly associated with MSI. (I) Lollipop charts of the mutation landscape of TFAP2A, showing a somatic mutation rate is 0.98%. (J) Protein expression of TFAP2A in normal and LUAD tissues in pathological sections, indicating that TFAP2A was highly expressed in LUAD samples.