Research Paper Volume 15, Issue 6 pp 1918—1930

Haplotype-GGGT in long non-coding RNA MALAT1 inhibits brain metastatic lung cancer and lymph nodes of lung cancer via the MALAT1/miR-328/KATNB1

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Figure 6. Knockdown of MALAT1 and overexpression of miR-328 suppressed the expression of KATNB1 in A549 and H460 cells (*p value < 0.05 compared with NC group). (A) The expression of MALAT1 was inhibited by MALAT1 siRNA and miR-328 precursors in A549 cells. (B) The expression of miR-328 was activated by MALAT1 siRNA and miR-328 precursors in A549 cells. (C) The expression of KATNB1 mRNA was inhibited by MALAT1 siRNA and miR-328 precursors in A549 cells. (D) The expression of MALAT1 was inhibited by MALAT1 siRNA and miR-328 precursors in H460 cells. (E) The expression of miR-328 was activated by MALAT1 siRNA and miR-328 precursors in H460 cells. (F) The expression of KATNB1 mRNA was inhibited by MALAT1 siRNA and miR-328 precursors in H460 cells.