Research Paper Volume 15, Issue 6 pp 2115—2135

Pan-cancer analysis reveals the associations between MMP13 high expression and carcinogenesis and its value as a serum diagnostic marker


Figure 7. Evaluation of the diagnostic efficacy of serum MMP13. (A) Scatter plot analysis of serum concentrations of MMP13 in patients with LUAD and controls. (B) Serum MMP13 ROC curves for samples from patients with LUAD and control subjects. (C) Youden index and cut-off value in LUAD to serum MMP13 concentration. (D) Sensitivity and specificity in LUAD to serum MMP13 concentration. (EH) Diagnostic tests for LUSC patients. (IL) Diagnostic tests for BRCA patients. (MP) Diagnostic tests for HNSC patients. The Mann-Whitney U-test was used for comparisons between the two groups. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.