Research Paper Volume 15, Issue 6 pp 2347—2357

MiR-320b aberrant expression enhances the radioresistance of human glioma via upregulated expression of ALDH1A3

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Figure 1. ALDH1A3 was highly expressed in high-grade glioma. (A) ALDH1A3 expression in different WHO grades of glioma based on the CGGA database. (B) The Kaplan-Meier analysis of the CGGA database revealed that glioma patients with increased ALDH1A3 expression had a lower overall survival rate. (C) ALDH1A3 was highly enriched in glioma tissue compared with adjacent normal tissue. (D) Elevated expression of ALDH1A3 was observed in GBM cell lines compared to human cortical neurons (HCN2). *p < 0.05, **p < 0.01.