Research Paper Volume 15, Issue 7 pp 2525—2540

RNA helicase DDX5-induced circPHF14 promotes gastric cancer cell progression

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Figure 1. DDX5 expression is correlated with poor patient survival in gastric cancer. (A) The expression of DDX5 was analyzed in patients with gastric. DDX5 expression in gastric cancer samples and non-cancer controls; the publicly accessible gene expression data of DDX5 was obtained from Oncomine database. (B) DDX5 expression in gastric cancer samples and non-cancer controls; The publicly accessible gene expression data of DDX5 was obtained from The Cancer Genome Atlas (TCGA) database. (C) Kaplan-Meier overall survival curves according to DDX5 expression in patient cohorts in KM-plotter database. The percentage of survival patients in high DDX5 and low DDX5 groups at different time points are presented. (D) DDX5 expression in gastric cancer patient with or non-cancer controls was measured by immunohistochemical staining. The publicly accessible protein expression data of DDX5 was obtained from The Human Protein Atlas database. Data were analyzed with Student’s t-test, p values were shown. Scale bar 200μm.