Research Paper Volume 15, Issue 9 pp 3410—3426

Development and validation of a novel anoikis-related gene signature for predicting prognosis in ovarian cancer

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Figure 6. Representative results of pathway analysis. (A) Volcano plot displayed DEGs between the HRrisk and LRisk subgroups (FDR<0.05, |log2 fold-change|>0.5). (B, C) Gene Ontology (GO) enrichment analysis of 322 genes up-regulated in the HRisk group (B) and 101 genes up-regulated in the LRisk group (C). (D, E) GSEA analysis of KEGG gene sets in the HRisk (D) and LRisk (E) subgroups (FDR<0.25). (F) GSVA analysis of hallmark pathways in the TCGA cohort was performed. Differential analysis of GSVA score between HRisk and LRisk group were displayed and FDR<0.01 were controlled.