Research Paper Volume 15, Issue 7 pp 2433—2449

Viral vector-mediated upregulation of serine racemase expression in medial prefrontal cortex improves learning and synaptic function in middle age rats


Figure 4. Upregulation of SR increased NMDAR-mediated synaptic response. Input-output curve of NMDAR-fEPSP in slices obtained from LV-SR (n = 8/4 slices/animals) and LV-GFP (n = 8/4 slices/animals) rats, plotting the mean SEM slope across animals relative to increasing stimulation intensities. *indicates a significant treatment difference at higher stimulation intensities (16–40V).