Research Paper Volume 15, Issue 9 pp 3538—3548
m6A-mediated upregulation of lncRNA-AC026356.1 promotes cancer stem cell maintenance in lung adenocarcinoma via activating Wnt signaling pathway
Figure 6. AC026356.1 is required for the self-renewal of cancer stem cell. (A) GSEA enrichment results show that AC026356.1 was involved in the Wnt signaling pathway. (B) Correlation between AC026356.1 and CD133, CD44, SOX2 and OCT4 in LUAD. (C, D) AC026356.1 knockdown repression significantly attenuated sphere formation of lung cancer cells. (E, F) The gene regulation by the lncRNA-miRNA-mRNA ceRNA network in the progression of LUAD. ***p < 0.001.