Research Paper Volume 15, Issue 10 pp 4182—4201

Sig1R activates extracellular matrix-induced bladder cancer cell proliferation and angiogenesis by combing β-integrin


Figure 1. Preparation and characterization of BEM. (A) Schematic illustration of bladder extracellular matrix (BEM) preparation and application. (B) Gross view of a bladder after decellularization. (C) H&E and Masson’s staining for BEM, scale bar = 100 μm. (D) Immunofluorescence of BEM proteins (collagen I, collagen III, fibronectin, and laminin), scale bar = 100 μm. (E) Quantification of DNA and GAG content in native bladder and BEM.