Research Paper Volume 15, Issue 10 pp 4391—4410

Hairy gene homolog increases nasopharyngeal carcinoma cell stemness by upregulating Bmi-1

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Figure 1. Bmi-1 was markedly upregulated in NPC clinical tissue specimens. (A) Bmi-1 levels were detected using qRT-PCR in the NPC cell lines shown. (B) Representative photographs from immunohistochemical analyses of Bmi-1 protein levels in NPC tissues and non-cancerous nasopharyngeal epithelial tissues. (C) Bmi-1 levels were significantly greater in NPC tissues than in non-cancerous nasopharyngeal epithelial tissues (P < 0.001, χ2 test).