Research Paper Volume 15, Issue 10 pp 4411—4428

Brevilin A shows an anti-tumor role in prostate cancer via the lncRNA H19/miR-194/E2F3 signaling pathway

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Figure 2. The impact of Brevilin A on lncRNA H19, miR-194, and E2F3 expressions. DU145 cells were treated at the concentrations of 10 μM and 20 μM, which were calculated through the IC50 values of Brevilin A. (AI) qRT-PCR determined lncRNA H19 (AC), miR-194 (DF) and E2F3 mRNA (GI) expressions. (JL) Western blot measured E2F3 expression. *P < 0.05, **P < 0.01, ***P < 0.001 (vs. control), n = 3.