**Figure 5.** **Construction of the prognostic model.** (**A**, **B**) The LASSO regression analysis and partial likelihood deviance on the prognostic genes. (**C**) Forest plot of the multivariate cox regression analysis for the six signature genes. (**D**) Sankey diagram demonstrated the distribution of TRG subtypes, gene subtypes, risk groups and survival status in SKCM patients. (**E**, **F**) Differences in risk score between the two TRG clusters and two gene clusters. (**G**) Differences in expression levels of TRGs in the two risk groups. (**H**) Heatmap illustrating the expression of six signature genes in the two risk groups in the testing cohort. (**I**) Risk score and survival outcome of each sample. Forest plots of univariate (**J**) and multivariate (**K**) Cox regression analyses in SKCM patients. ^{*}*p* < 0.05; ^{**}*p* < 0.01; ^{***}*p* < 0.001.