Research Paper Volume 15, Issue 10 pp 4465—4480
Identification and validation of diagnostic signature genes in non-obstructive azoospermia by machine learning
Figure 7. Animal NOA model construction and experiment validation in testis (NOA: irradiation-induced non-obstructive azoospermia mice, Control: control group). (A) Photographs of testis and epididymis. (B) Testis weight (g). (C) Sperm progressive motility results (PR). (D) Total sperm motility results (Total). (E) Relative mRNA expression of SPO11, SYCP2, PRM3, TNP1. (F) Testicular HE staining results (4×, 10×, 40×field). (G) Relative mRNA expression of signature genes (C12orf54, TSSK6, OR2H1, FER1L5, C9orf153) in testis. (**indicates P < 0.01, ***indicates P < 0.001, ****indicates P < 0.0001).