Research Paper Volume 15, Issue 12 pp 5426—5444

Chaetocin exhibits anticancer effects in esophageal squamous cell carcinoma via activation of Hippo pathway


Figure 1. Chaetocin suppresses the growth of ESCC cells. (A, B) TE-1 and KYSE150 cells were treated with the indicated concentrations of chaetocin (0, 0.2, 0.4, and 0.8 μM) for 24 h. The cell viability was examined by CCK-8. The colony formation was evaluated after 14 days. (C) EdU assay was used to measure cell proliferation. The results are presented as the mean ± SD and are representative of at least three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001 compared with the control group.