Research Paper Volume 15, Issue 12 pp 5426—5444

Chaetocin exhibits anticancer effects in esophageal squamous cell carcinoma via activation of Hippo pathway

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Figure 1. Chaetocin suppresses the growth of ESCC cells. (A, B) TE-1 and KYSE150 cells were treated with the indicated concentrations of chaetocin (0, 0.2, 0.4, and 0.8 μM) for 24 h. The cell viability was examined by CCK-8. The colony formation was evaluated after 14 days. (C) EdU assay was used to measure cell proliferation. The results are presented as the mean ± SD and are representative of at least three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001 compared with the control group.