Research Paper Volume 15, Issue 12 pp 5550—5568

Mettl3-mediated m6A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression


Figure 6. Adh7 and Cpt1a are the potential targets modified by Mettl3-mediated m6A modification in regulating liver lipid metabolism. (A, B) Peak distribution normalized to input in the genomic regions of Adh7 (A) and Cpt1a (B) in control and METTL3 HKO mice in the GSE179680 dataset. (C, D) Schematic representation of predicted positions of m6A motifs within Adh7 (C) and Cpt1a (D) mRNA.