Research Paper Volume 15, Issue 12 pp 5751—5774

Construction of a T-cell exhaustion-related gene signature for predicting prognosis and immune response in hepatocellular carcinoma

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Figure 9. FTL promoted proliferation in HCC. (A) TCGA database analysis indicated that FTL mRNA expression is increased in HCC. (B) Immunohistochemical results suggest that FTL is highly expressed in tumor tissues. (C) Western blot analysis confirmed that the expression of FTL was inhibited by SIRNA. (D) CCK8 assay indicated that FTL inhibition significantly suppressed the proliferation in HCC cells. (E) EdU assays indicated that FTL inhibition significantly suppressed the proliferation in HCC cells. *P < 0.05, **P < 0.01, ***P < 0.001.