Research Paper Volume 15, Issue 13 pp 6302—6330
Clinical significance, tumor immune landscape and immunotherapy responses of ADAR in pan-cancer and its association with proliferation and metastasis of bladder cancer
Figure 3. Interaction network of ADAR and enrichment analysis of related genes. (A) 50 experimentally verified ADAR interacting genes obtained from the String database. (B) A heat map of the specific associations of the five most highly correlated ADAR genes (EIF2AK2, ISG20L2, SMG7, UBAP2L, and YY1AP1) in pan-cancer. (C) EIF2AK2 was the most critical gene. We also presented correlations for EIF2AK2 and four additional significantly associated genes. (D) GO and KEGG enrichment analyses for all ADAR-related genes. (E) GSEA enrichment analysis revealed the molecular pathways of ADAR-related genes.