Combined surface functionalization of MSC membrane and PDA inhibits neurotoxicity induced by Fe<sub>3</sub>O<sub>4</sub> in mice based on apoptosis and autophagy through the ASK1/JNK signaling pathway

Yang Li; Te Liu; Xiuying Li; Modi Yang; Tianxin Liu; Jindian Bao; Miao Jiang; Lingling Hu; Yuzhuo Wang; Pu Shao; Jinlan Jiang

doi:doi:10.18632/aging.204884

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Research Paper Volume 15, Issue 14 pp 6933—6949

Combined surface functionalization of MSC membrane and PDA inhibits neurotoxicity induced by Fe₃O₄ in mice based on apoptosis and autophagy through the ASK1/JNK signaling pathway

Figure 1. Characterization of Fe₃O₄, Fe₃O₄@PDA and MSCM-Fe₃O₄@PDA NPs. (A) TEM images of NPs. (B) DLS of NPs. (C) Zeta potential of NPs. (D) Stability analysis of NPs. (E) SDS-PAGE protein analysis of Fe₃O₄@PDA, Cell lysate, MSC membrane and MSCM-Fe₃O₄@PDA. (F) Membrane protein expressions of Fe₃O₄@PDA, Cell lysate, MSC membrane and MSCM-Fe₃O₄@PDA.

Research Paper Volume 15, Issue 14 pp 6933—6949

Combined surface functionalization of MSC membrane and PDA inhibits neurotoxicity induced by Fe3O4 in mice based on apoptosis and autophagy through the ASK1/JNK signaling pathway

Combined surface functionalization of MSC membrane and PDA inhibits neurotoxicity induced by Fe₃O₄ in mice based on apoptosis and autophagy through the ASK1/JNK signaling pathway