Research Paper Volume 15, Issue 15 pp 7440—7450
hsa_circ_0010889 downregulation inhibits malignant glioma progression by modulating the miR-590-5p/SATB1 axis
Figure 1. hsa_circ_0010889 plays a key role in the progression of glioma. (A) Heat map showing the expression of circRNA in CRC tumor tissues and adjacent normal tissues. (B) RT-qPCR detection shows the expression of five highly expressed circRNAs in glioma tumor tissues and adjacent normal tissues. The data are presented as the mean ± SD. ***p < 0.001 vs. Normal. (C) RT-qPCR detection showing the expression of hsa_circ_0010889 in the glioma cell lines LN229, SHG44, U251, and T98G and the normal glial cell line HEB. The data are presented as the mean ± SD. **p < 0.01 vs. HEB. (D) FISH detection showing the expression and subcellular distribution of hsa_circ_0010889.