Research Paper Volume 15, Issue 15 pp 7593—7615
Development of tryptophan metabolism patterns to predict prognosis and immunotherapeutic responses in hepatocellular carcinoma
Figure 1. The genetic alterations and transcriptional expression of TRPGs in HCC. (A) The mutation frequencies and distribution of 42 TRPGs in the TCGA HCC cohort. (B) Frequencies of CNV alterations of TRPGs in HCC. (C) Locations of CNV alterations in TRPGs on chromosomes. (D) Expression distributions of 42 TRPGs between HCC tumor and normal tissues. *p<0.05, **p < 0.01, ***p < 0.001. TRPGs, tryptophan metabolism-related genes; HCC, hepatocellular carcinoma; TCGA, The Cancer Genome Atlas; CNV, copy number variation.