Research Paper Volume 15, Issue 21 pp 11845—11859
Capsaicin alleviates doxorubicin-induced acute myocardial injury by regulating iron homeostasis and PI3K-Akt signaling pathway
Figure 4. CAP mitigated DOX-induced ferroptosis in mice. (A) Immunoprotein gel of COX-2, SLC7All, FTHI, GPX4 in mice (n = 3). (B) Relative expressions of COX-2, SLC7All, FTHI, GPX4 in mice. (C) Immunoprotein gel of Trf and SLC40A1 in mice (n = 3). (D) Relative expression levels of Trf and SLC40A1 in mice (n = 3). Data are shown as the mean ± SEM. Statistical significance was determined using two-tailed student’s t-test. *p < 0.05, **p < 0.01, ***p < 0.001.