Research Paper Volume 15, Issue 21 pp 11970—11984
Identification of epithelial-mesenchymal transition-related biomarkers in lung adenocarcinoma using bioinformatics and lab experiments
Figure 2. Validation of the EMT-associated gene signature. (A–E) The 5-year AUC of the gene signature for predicting overall survival (OS) was 0.668, 0.702, 0.774, 0.756, and 0.669 in the training set, the validation set and the external test sets, respectively. (F–H) The 5-year AUC of the gene signature for predicting progression free survival (PFS) was 0.774, 0.746, and 0.755 in three external test sets, respectively. (I–K) The high-risk scores were associated with poor survival outcomes and high expression levels of the eight genes in the GSE8894 cohort, the GSE50081 cohort, and the GSE30219 cohort.